Memantine will not cure Alzheimer's disease, and it will not stop the disease from getting worse. Call your doctor for medical advice about side effects. All rights reserved. It works by decreasing abnormal activity in the brain. Symptoms and warning signs of Alzheimer's disease include memory loss, difficulty performing familiar tasks, disorientation to time and place, misplacing things, and more. Other conditions and medication reactions can also cause dementia. Consult your pharmacist or local waste disposal company.Information last revised October 2018. The dose usually is increased to 5 mg twice daily, then 5 mg and 10 mg as © 2005 - 2019 WebMD LLC. Many people using this medication do not have serious side effects. Rinse the syringe with water after each use. Memantine (Namenda) and a combination of memantine and donepezil (Namzaric®) are approved by the FDA for treatment of moderate to severe Alzheimer’s. These drugs - galantamine ( Razadyne - formerly known as Reminyl), donezepil ( Aricept ), rivastigmine ( Exelon ), and tacrine (Cognex) - … Capsules may be swallowed whole or opened and sprinkled on spoonsful Otherwise, call a poison control center right away. The disease Alzheimer's is not curable but it can be managed by this specific drug. Consult your doctor before breast-feeding. Read on to learn more about this drug, its mechanisms, side-effects, and more! Memantine uses, as this eMedTV page explains, are primarily concerned with treating moderate to severe dementia in people with Alzheimer's disease. Memantine may improve the ability to think and remember or may slow the loss of these abilities in people who have AD. If you are taking memantine oral liquid, read the manufacturer's instruction sheet that comes with the bottle. Known by the trade name Namenda, it has been shown to be moderately effective for preventing the progression of the symptoms of some types of dementia. Preparing financially for someone with Alzheimer's disease is an important task to complete so that bills get paid and the best coverage is provided. If you forget to take memantine for several days, talk to your doctor before your next dose. Memantine, also known under the drug name Namenda, is a powerful nootropic that was first created in 1968 and is used as a prescription drug in the U.S. and Europe for the treatment of moderate to severe Alzheimer’s disease (AD). It can be used alone or with other Alzheimer’s disease treatments. However, the … Some doctors and researchers disagree in regard to the number of stages of Alzheimer's disease (from It is at times also used to improve general pain or parkinson disease. This drug may make you dizzy. Namenda (memantine) reduces the actions of chemicals in the brain that may contribute to the symptoms of Alzheimer's disease. Take your medicine as directed. Drug interactions may change how your medications work or increase your risk for serious side effects. Memantine is in a class of medications called NMDA receptor antagonists. using the bathroom. The most common side effects of memantine are: Memantine may cause a serious skin reaction called Stevens-Johnson syndrome. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Memantine is intended to prevent an excess of glutamate from damaging the brain. It is at times also used to improve general pain or parkinson disease. Swallow the medication directly from the syringe. Glutamate is a neurotransmitter, in other words, a substance that sends messages to neural signals. Doctor: Checklist to Take To Your Doctor's Appointment, Drugs: Buying Prescription Drugs Online Safely. Your dose may need to be changed several times to find what works best for you. What is Memantine (Namenda)? These. What should I know regarding pregnancy, nursing and administering Memantine HCL to children or the elderly? What is memantine, and how does it work (mechanism of action)? This page describes the drug's effects, explains how it works, and discusses possible off-label uses. or without food. Medically reviewed by John P. Cunha, DO, FACOEP; Board Certified Emergency Medicine. Talk to your pharmacist for more details. Memantine uses. Memantine is used to treat the symptoms of Alzheimer's disease (AD; a brain disease that slowly destroys the memory and the ability to think, learn, communicate and handle daily activities). US residents can call their local poison control center at 1-800-222-1222. Although memantine is not the first NMDA antagonist used to target migraines, it is one of the first with a low side-effect profile that has been shown to be efficacious. Memantine is a prescription medication used to treat Alzheimer's disease. Like other neurotransmitters, glutamate is produced and released by nerve cells in the brain. This document does not contain all possible drug interactions. Memantine is prescribed to improve memory, attention, reason, language and the ability to perform simple tasks. It is thought that by blocking the NMDA receptor and the effects of glutamate, memantine may protect nerve cells from excess stimulation by glutamate. Copyright(c) 2018 First Databank, Inc. Are you considering switching to Memantine HCL? MedicineNet does not provide medical advice, diagnosis or treatment. Memantine is not a cure for Alzheimer's disease but it can help people with the disease. Learn the early warning signs and symptoms of Alzheimer's disease. Memantine is used to treat moderate to severe dementia of the Alzheimer's type. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Memantine is used to treat moderate to severe Alzheimer's disease. Alzheimer's disease is a common cause of dementia. It can slow progression of symptoms in Alzheimer’s disease, like disorientation. Memantine is used for the treatment of moderate to While the drug is not a cure, it can help improve memory, attention, reason, language, and the ability to perform simple daily tasks. Some products that may interact with this drug include: carbonic anhydrase inhibitors (such as acetazolamide, methazolamide), sodium bicarbonate. mg daily. When you first start taking this medication, you will usually take it once daily. of applesauce. Mental health is an optimal way of thinking, relating to others, and feeling. It is unknown if this drug passes into breast milk. One of the first symptoms of Alzheimer's disease is __________________. It is taken by mouth. example, carbonic anhydrase inhibitors such as. You are encouraged to report negative side effects of prescription drugs to the FDA. It is less preferred than acetylcholinesterase inhibitors such as donepezil. Learn about dementia disorders such as Lewy Body Dementia, Alzheimer's disease (AD), Vascular (multi-infarct)... Use this guide for advice on caring for someone with Alzheimer's. Depression, anxiety, and substance-abuse disorders are common types of mental illness. The released glutamate then travels to nearby nerve cells where it attaches to a receptor on the surface of the cells called the N-methyl-D-aspartate (NMDA) receptor. Take the Alzheimer's Quiz to discover some of the mysteries behind this cognitive disorder. Do not use a household spoon because you may not get the correct dose. It was first developed in the 1960s for the treatment of diabetes. The amount of medicine that you take depends on the strength of the medicine. Take your next dose at the regular time. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. example, It is not known if memantine is excreted into. Memantine may also be used for purposes not listed in this medication guide. Namenda (also called Memantine) was approved by the FDA in 2003 for use in people with “moderate to severe” Alzheimer’s disease or other types of dementia. Things to remember when you fill your prescription. The Global Deterioration Scale or GDS identifies seven stages of Alzheimer's disease that include stage 1 (no impairment), stage 2 (very Other medications used for Alzheimer's disease affect acetylcholine, one of the neurotransmitter chemicals that nerve cells in the brain use to communicate with one another. Namenda is used to treat moderate to severe dementia of the Alzheimer's type. Body aches, dizziness, constipation, and headache may occur. Memantine (Namenda, Namenda XR) is a medication prescribed for treating patient's with Alzheimer's disease and dementia. It does not cure Alzheimer's disease, but it may improve memory, awareness, and the ability to perform daily functions. Once your dose increases to more than 5 milligrams per day, take this medication twice daily or as directed by your doctor. Treatment for Alzheimer's is often targeted toward decreasing the symptoms and progression of the disease. Most people need to wait at least one week between dose changes. It works by decreasing abnormal activity in the brain. Dementia is defined as a significant loss of intellectual abilities such as memory capacity, severe enough to interfere with social or occupational functioning. Selected from data included with permission and copyrighted by First Databank, Inc. The dosage is based on your medical condition and response to treatment. You may report side effects to Health Canada at 1-866-234-2345. Generic Drugs, Are They as Good as Brand-Names? Memantine, commonly prescribed in the United States under the brand name Namenda, is for people with moderate-to-severe Alzheimer’s disease and vascular dementia. Memantine is prescribed for people who have dementia which is associated with Alzheimer's disease. Namenda may also be used for purposes not listed in this medication guide. Other medications used for Alzheimer's disease affect acetylcholine, one of the neurotransmitter chemicals that nerve cells in the brain use to communicate with one another. It is believed that too much stimulation of nerve cells by glutamate may be responsible for the degeneration of nerves that occurs in some neurological diseases such as Alzheimer's disease. F). 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